Comparison of Buprenorphine and Methadone Maintenance in Opiate Addicts (2024)

Skip Nav Destination

Article navigation

Volume 4, Issue Suppl. 1

October 1998

Research Articles| October 15 1998

Subject Area: Pharmacology , Psychiatry and Psychology , Public Health

Harald Eder;

Harald Eder

a Department of General Psychiatry, University Hospital of Psychiatry,

Search for other works by this author on:

This Site

Gabriele Fischer;

Gabriele Fischer

a Department of General Psychiatry, University Hospital of Psychiatry,

Search for other works by this author on:

This Site

Wolfgang Gombas;

Wolfgang Gombas

a Department of General Psychiatry, University Hospital of Psychiatry,

Search for other works by this author on:

This Site

Reinhold Jagsch;

Georg Stühlinger;

Georg Stühlinger

b University Clinic of Emergency Medicine, Währinger Gürtel, Vienna, Austria

Search for other works by this author on:

This Site

Siegfried Kasper

Siegfried Kasper

a Department of General Psychiatry, University Hospital of Psychiatry,

Search for other works by this author on:

This Site

Eur Addict Res (1998) 4 (Suppl. 1): 3–7.

Article history

Published Online:

October 15 1998

Content Tools

  • Views Icon Views
    • Article contents
    • Figures & tables
    • Video
    • Audio
    • Supplementary Data
    • Peer Review
  • Tools Icon Tools
  • Search Site

Citation

Harald Eder, Gabriele Fischer, Wolfgang Gombas, Reinhold Jagsch, Georg Stühlinger, Siegfried Kasper; Comparison of Buprenorphine and Methadone Maintenance in Opiate Addicts. Eur Addict Res 1 October 1998; 4 (Suppl. 1): 3–7. https://doi.org/10.1159/000052034

Download citation file:

  • Ris (Zotero)
  • Reference Manager
  • EasyBib
  • Bookends
  • Mendeley
  • Papers
  • EndNote
  • RefWorks
  • BibTex
toolbar search

Search Dropdown Menu

Advanced Search

Abstract

As a maintenance agent for opioid dependency, buprenorphine offers advantages such as a lower level of dependence and minimal withdrawal symptoms, due to its partial agonist properties at the µ-opioid receptor. Previous studies have shown 8mg sublingual buprenorphine to be equivalent to 60mg oral methadone in terms of retention rate and opioid-negative urine levels. In a 24-week, ongoing European study, 34 opioid-dependent subjects were assessed; 16 receiving buprenorphine and 18 methadone. A free dosing schedule was used with no upper limit for methadone dosing but with a maximum buprenorphine dose of 8mg. Screening prior to the study excluded subjects with polysubstance dependence, somatic disease and/or HIV infection. Primary outcome measures were abstinence from other drugs, for which subjects provided weekly urine samples for analysis of opioids, cocaine and benzodiazepines, and retention in treatment. Patients in the buprenorphine group provided a greater proportion of negative urine samples, in particular cocaine-negative samples, compared with the methadone group, although this was not statistically significant. Retention in the buprenorphine group was significantly lower than in the methadone group, suggesting that the 8 mg buprenorphine limit may have biased the results in favour of methadone, and that this dose may have been too low for those subjects with high levels of dependence. However, buprenorphine is clearly effective in the more motivated subjects and further investigation in this subgroup is recommended.

Keywords:

Buprenorphine, Maintenance therapy, Drug addiction, Methadone

This content is only available via PDF.

1998

Copyright / Drug Dosage / Disclaimer

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.

Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.

Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisem*nts or/and product references in the publication is not a warranty, endorsem*nt, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisem*nts.

You do not currently have access to this content.

Sign in

Don't already have an account? Register

Individual Login

LOGIN TO MY KARGER

Institutional Login

  • Access via Shibboleth and OpenAthens
  • Access via username and password

Digital Version

Pay-Per-View Access

$39.00

BUY THIS Article

1 Karger Article Bundle Token

$150

Buy Token

Rental

This article is also available for rental through DeepDyve. Comparison of Buprenorphine and Methadone Maintenance in Opiate Addicts (2)

40 Views

42 Web of Science

37 Crossref

View Metrics

×

Email alerts

Online First Alert

Latest Issue Alert

Close Modal

Citing articles via

Google Scholar

CrossRef (37)

  • Latest
  • Most Read
  • Most Cited

Another Round: Influence of Alcohol-Related Conditions and Other Drug Use-Related Disorders in Emergency Department Frequent Use – A Single-Site Matched Case-Control Study in Spain

The Role of Perceived Stress in the Relation between Childhood Maltreatment and Severity of Alcohol Use Disorder: A Mediation Analysis

Treatment Seeking Nitrous Oxide Users in Addiction Care: A Comparison with Cocaine Users on Clinical and Treatment Characteristics

European Portuguese Version of the Game Addiction Scale-7: Factor Structure and Psychometric Properties

Transcranial Direct Current Stimulation for Food Craving in Women Affected by Overweight and Obesity: A Randomized Controlled Trial

Suggested Reading

Buprenorphine Maintenance in Pregnant Opiate Addicts

Eur Addict Res (October,1998)

Comparison of Buprenorphine and Methadone in the Treatment of Opioid Dependence: Swiss Multicentre Study

Eur Addict Res (October,1998)

Substitution with Buprenorphine in Methadone- and Morphine Sulfate-Dependent Patients: Preliminary Results

Eur Addict Res (October,1998)

Alcohol Use Disorders in Opioid Maintenance Therapy: Prevalence, Clinical Correlates and Treatment

Eur Addict Res (January,2015)

Comparison of Buprenorphine and Methadone Maintenance in Opiate Addicts (2024)
Top Articles
How do you cook wild boar? - Chef's Resource
How to Cook Wild Boar - OutdoorsChef
Tyler Sis 360 Louisiana Mo
Chase Bank Operating Hours
Umn Pay Calendar
Midway Antique Mall Consignor Access
A.e.a.o.n.m.s
What Does Dwb Mean In Instagram
Gma Deals And Steals Today 2022
Chile Crunch Original
Google Feud Unblocked 6969
Conscious Cloud Dispensary Photos
Costco Gas Foster City
24 Hour Drive Thru Car Wash Near Me
Persona 4 Golden Taotie Fusion Calculator
Ratchet & Clank Future: Tools of Destruction
FDA Approves Arcutis’ ZORYVE® (roflumilast) Topical Foam, 0.3% for the Treatment of Seborrheic Dermatitis in Individuals Aged 9 Years and Older - Arcutis Biotherapeutics
Chaos Space Marines Codex 9Th Edition Pdf
Encore Atlanta Cheer Competition
Like Some Annoyed Drivers Wsj Crossword
Www Va Lottery Com Result
Gotcha Rva 2022
Trivago Myrtle Beach Hotels
D2L Brightspace Clc
Shelby Star Jail Log
Dhs Clio Rd Flint Mi Phone Number
Duke University Transcript Request
Funky Town Gore Cartel Video
Eegees Gift Card Balance
Allegheny Clinic Primary Care North
Bfri Forum
Roch Hodech Nissan 2023
Supermarkt Amsterdam - Openingstijden, Folder met alle Aanbiedingen
Back to the Future Part III | Rotten Tomatoes
Bay Focus
Soulstone Survivors Igg
Bbc Gahuzamiryango Live
The TBM 930 Is Another Daher Masterpiece
Citibank Branch Locations In Orlando Florida
Armageddon Time Showtimes Near Cmx Daytona 12
Unblocked Games Gun Games
Senior Houses For Sale Near Me
FedEx Authorized ShipCenter - Edouard Pack And Ship at Cape Coral, FL - 2301 Del Prado Blvd Ste 690 33990
Holzer Athena Portal
Enter The Gungeon Gunther
Espn Top 300 Non Ppr
The Quiet Girl Showtimes Near Landmark Plaza Frontenac
Dineren en overnachten in Boutique Hotel The Church in Arnhem - Priya Loves Food & Travel
Compete My Workforce
Dumb Money Showtimes Near Regal Stonecrest At Piper Glen
Invitation Quinceanera Espanol
Craigslist Centre Alabama
Latest Posts
Article information

Author: Stevie Stamm

Last Updated:

Views: 5876

Rating: 5 / 5 (60 voted)

Reviews: 91% of readers found this page helpful

Author information

Name: Stevie Stamm

Birthday: 1996-06-22

Address: Apt. 419 4200 Sipes Estate, East Delmerview, WY 05617

Phone: +342332224300

Job: Future Advertising Analyst

Hobby: Leather crafting, Puzzles, Leather crafting, scrapbook, Urban exploration, Cabaret, Skateboarding

Introduction: My name is Stevie Stamm, I am a colorful, sparkling, splendid, vast, open, hilarious, tender person who loves writing and wants to share my knowledge and understanding with you.